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Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions
Noonan syndrome is an autosomal dominant developmental disorder. Although it is relatively common, and its phenotypical variability is well documented, its pathophysiology is not fully understood. Previously, with the aim of revealing the pathogenesis of genetic disorders, we reported the induction...
Autores principales: | Hamada, Atsuko, Akagi, Eri, Obayashi, Fumitaka, Yamasaki, Sachiko, Koizumi, Koichi, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Toratani, Shigeaki, Okamoto, Tetsuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723931/ https://www.ncbi.nlm.nih.gov/pubmed/33140329 http://dx.doi.org/10.1007/s11626-020-00515-9 |
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