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Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study

OBJECTIVES: To investigate the risk of hospitalized fall or hip fracture among older adults using mental health services. DESIGN: Retrospective cohort study. SETTING AND PARTICIPANTS: Residents of a South London catchment aged >60 years receiving specialist mental health care between 2008 and 201...

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Autores principales: Stubbs, Brendon, Perara, Gayan, Koyanagi, Ai, Veronese, Nicola, Vancampfort, Davy, Firth, Joseph, Sheehan, Katie, De Hert, Marc, Stewart, Robert, Mueller, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723983/
https://www.ncbi.nlm.nih.gov/pubmed/32321678
http://dx.doi.org/10.1016/j.jamda.2020.03.005
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author Stubbs, Brendon
Perara, Gayan
Koyanagi, Ai
Veronese, Nicola
Vancampfort, Davy
Firth, Joseph
Sheehan, Katie
De Hert, Marc
Stewart, Robert
Mueller, Christoph
author_facet Stubbs, Brendon
Perara, Gayan
Koyanagi, Ai
Veronese, Nicola
Vancampfort, Davy
Firth, Joseph
Sheehan, Katie
De Hert, Marc
Stewart, Robert
Mueller, Christoph
author_sort Stubbs, Brendon
collection PubMed
description OBJECTIVES: To investigate the risk of hospitalized fall or hip fracture among older adults using mental health services. DESIGN: Retrospective cohort study. SETTING AND PARTICIPANTS: Residents of a South London catchment aged >60 years receiving specialist mental health care between 2008 and 2016. MEASURES: Falls and/or a hip fracture leading to hospitalization were ascertained from linked national records. Incidence rates and incidence rate ratios (IRRs) were age- and gender-standardized to the catchment population. Multivariable survival analyses were applied investigating falls and/or hip fractures as outcomes. RESULTS: In 22,103 older adults, incidence rates were 60.1 per 1000 person-years for hospitalized falls and 13.7 per 1000 person-years for hip fractures, representing standardized IRRs of 2.17 [95% confidence interval (CI) 2.07-2.28] and 4.18 (3.79-4.60), respectively. The IRR for falls was high in those with substance-use disorder [IRR = 6.72 (5.35-8.33)], bipolar disorder [IRR = 3.62 (2.50-5.05)], depression [IRR = 2.28 (2.00-2.59)], and stress-related disorders [IRR = 2.57 (2.10-3.11)]. Hip fractures were increased in all populations (IRR > 2.5), with greatest risk in substance use disorders [IRR = 12.64 (7.22-20.52)], dementia [IRR = 4.38 (3.82-5.00)], and delirium [IRR = 4.03 (3.00-5.29)]. Comparing mental disorder subgroups with each other, after the adjustment for 25 potential confounders, patients with dementia and substance use had a significantly increased risk of falls, and patients with dementia also had an increased risk of hip fractures. CONCLUSION AND IMPLICATIONS: Older people using mental health services have more than double the incidence of falls and 4 times the incidence of hip fractures compared to the general population. Although incidences differ between diagnostic subgroups, all groups have a higher incidence than the general population. Targeted interventions to prevent falls and hip fractures among older adult mental health service users are urgently needed.
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spelling pubmed-77239832020-12-11 Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study Stubbs, Brendon Perara, Gayan Koyanagi, Ai Veronese, Nicola Vancampfort, Davy Firth, Joseph Sheehan, Katie De Hert, Marc Stewart, Robert Mueller, Christoph J Am Med Dir Assoc Original Study OBJECTIVES: To investigate the risk of hospitalized fall or hip fracture among older adults using mental health services. DESIGN: Retrospective cohort study. SETTING AND PARTICIPANTS: Residents of a South London catchment aged >60 years receiving specialist mental health care between 2008 and 2016. MEASURES: Falls and/or a hip fracture leading to hospitalization were ascertained from linked national records. Incidence rates and incidence rate ratios (IRRs) were age- and gender-standardized to the catchment population. Multivariable survival analyses were applied investigating falls and/or hip fractures as outcomes. RESULTS: In 22,103 older adults, incidence rates were 60.1 per 1000 person-years for hospitalized falls and 13.7 per 1000 person-years for hip fractures, representing standardized IRRs of 2.17 [95% confidence interval (CI) 2.07-2.28] and 4.18 (3.79-4.60), respectively. The IRR for falls was high in those with substance-use disorder [IRR = 6.72 (5.35-8.33)], bipolar disorder [IRR = 3.62 (2.50-5.05)], depression [IRR = 2.28 (2.00-2.59)], and stress-related disorders [IRR = 2.57 (2.10-3.11)]. Hip fractures were increased in all populations (IRR > 2.5), with greatest risk in substance use disorders [IRR = 12.64 (7.22-20.52)], dementia [IRR = 4.38 (3.82-5.00)], and delirium [IRR = 4.03 (3.00-5.29)]. Comparing mental disorder subgroups with each other, after the adjustment for 25 potential confounders, patients with dementia and substance use had a significantly increased risk of falls, and patients with dementia also had an increased risk of hip fractures. CONCLUSION AND IMPLICATIONS: Older people using mental health services have more than double the incidence of falls and 4 times the incidence of hip fractures compared to the general population. Although incidences differ between diagnostic subgroups, all groups have a higher incidence than the general population. Targeted interventions to prevent falls and hip fractures among older adult mental health service users are urgently needed. Elsevier 2020-12 /pmc/articles/PMC7723983/ /pubmed/32321678 http://dx.doi.org/10.1016/j.jamda.2020.03.005 Text en © 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Study
Stubbs, Brendon
Perara, Gayan
Koyanagi, Ai
Veronese, Nicola
Vancampfort, Davy
Firth, Joseph
Sheehan, Katie
De Hert, Marc
Stewart, Robert
Mueller, Christoph
Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title_full Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title_fullStr Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title_full_unstemmed Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title_short Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study
title_sort risk of hospitalized falls and hip fractures in 22,103 older adults receiving mental health care vs 161,603 controls: a large cohort study
topic Original Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723983/
https://www.ncbi.nlm.nih.gov/pubmed/32321678
http://dx.doi.org/10.1016/j.jamda.2020.03.005
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