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An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation

The prevention and treatment of malaria requires a multi-pronged approach, including the development of drugs that have novel modes of action. Histone deacetylases (HDACs), enzymes involved in post-translational protein modification, are potential new drug targets for malaria. However, the lack of r...

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Detalles Bibliográficos
Autores principales: Hesping, Eva, Skinner-Adams, Tina S., Fisher, Gillian M., Kurz, Thomas, Andrews, Katherine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724001/
https://www.ncbi.nlm.nih.gov/pubmed/33279862
http://dx.doi.org/10.1016/j.ijpddr.2020.10.010