Cargando…
An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation
The prevention and treatment of malaria requires a multi-pronged approach, including the development of drugs that have novel modes of action. Histone deacetylases (HDACs), enzymes involved in post-translational protein modification, are potential new drug targets for malaria. However, the lack of r...
Autores principales: | Hesping, Eva, Skinner-Adams, Tina S., Fisher, Gillian M., Kurz, Thomas, Andrews, Katherine T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724001/ https://www.ncbi.nlm.nih.gov/pubmed/33279862 http://dx.doi.org/10.1016/j.ijpddr.2020.10.010 |
Ejemplares similares
-
Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice
por: Chua, Ming Jang, et al.
Publicado: (2021) -
Host histone acetylation unlocks HDAC inhibitor potential
por: Terranova-Barberio, Manuela, et al.
Publicado: (2017) -
Histone H3 lysine 27 acetylation is altered in colon cancer
por: Karczmarski, Jakub, et al.
Publicado: (2014) -
Histone 4 lysine 8 acetylation regulates proliferation and host–pathogen interaction in Plasmodium falciparum
por: Gupta, Archana P., et al.
Publicado: (2017) -
Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
por: Moreno-Yruela, Carlos, et al.
Publicado: (2022)