Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19

A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was conf...

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Detalles Bibliográficos
Autores principales: Woodhall, Mark, Mitchell, James W., Gibbons, Emily, Healy, Sarah, Waters, Patrick, Huda, Saif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724101/
https://www.ncbi.nlm.nih.gov/pubmed/33324337
http://dx.doi.org/10.3389/fneur.2020.598531
Descripción
Sumario:A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was confirmed by nasopharyngeal swab and MOG-IgG serological reversion was noted. Visual function improved following steroids and plasma exchange. This case highlights a possible causal association between inflammation due to COVID-19 and a relapse of MOG-IgG associated disease. It also highlights the clinical relevance of reporting MOG-IgG titers in MOG-IgG associated disease.

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