Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19

A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was conf...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodhall, Mark, Mitchell, James W., Gibbons, Emily, Healy, Sarah, Waters, Patrick, Huda, Saif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724101/
https://www.ncbi.nlm.nih.gov/pubmed/33324337
http://dx.doi.org/10.3389/fneur.2020.598531
_version_ 1783620479552061440
author Woodhall, Mark
Mitchell, James W.
Gibbons, Emily
Healy, Sarah
Waters, Patrick
Huda, Saif
author_facet Woodhall, Mark
Mitchell, James W.
Gibbons, Emily
Healy, Sarah
Waters, Patrick
Huda, Saif
author_sort Woodhall, Mark
collection PubMed
description A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was confirmed by nasopharyngeal swab and MOG-IgG serological reversion was noted. Visual function improved following steroids and plasma exchange. This case highlights a possible causal association between inflammation due to COVID-19 and a relapse of MOG-IgG associated disease. It also highlights the clinical relevance of reporting MOG-IgG titers in MOG-IgG associated disease.
format Online
Article
Text
id pubmed-7724101
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-77241012020-12-14 Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19 Woodhall, Mark Mitchell, James W. Gibbons, Emily Healy, Sarah Waters, Patrick Huda, Saif Front Neurol Neurology A 39-year-old lady with relapsing myelin oligodendrocyte glycoprotein antibody (MOG-IgG) associated disease developed coryzal symptoms, malaise, sweating, and postural dizziness. Six days later she presented with painful progressive right visual loss consistent with optic neuritis. COVID-19 was confirmed by nasopharyngeal swab and MOG-IgG serological reversion was noted. Visual function improved following steroids and plasma exchange. This case highlights a possible causal association between inflammation due to COVID-19 and a relapse of MOG-IgG associated disease. It also highlights the clinical relevance of reporting MOG-IgG titers in MOG-IgG associated disease. Frontiers Media S.A. 2020-11-25 /pmc/articles/PMC7724101/ /pubmed/33324337 http://dx.doi.org/10.3389/fneur.2020.598531 Text en Copyright © 2020 Woodhall, Mitchell, Gibbons, Healy, Waters and Huda. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Woodhall, Mark
Mitchell, James W.
Gibbons, Emily
Healy, Sarah
Waters, Patrick
Huda, Saif
Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title_full Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title_fullStr Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title_full_unstemmed Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title_short Case Report: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Relapse With COVID-19
title_sort case report: myelin oligodendrocyte glycoprotein antibody-associated relapse with covid-19
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724101/
https://www.ncbi.nlm.nih.gov/pubmed/33324337
http://dx.doi.org/10.3389/fneur.2020.598531
work_keys_str_mv AT woodhallmark casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19
AT mitchelljamesw casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19
AT gibbonsemily casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19
AT healysarah casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19
AT waterspatrick casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19
AT hudasaif casereportmyelinoligodendrocyteglycoproteinantibodyassociatedrelapsewithcovid19

Ejemplares similares