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A case of human rabies with a long incubation period in Wuhan
Rabies remains endemic in China and continues to pose a major threat to public health with a nearly 100 % case fatality rate in humans. We confirmed a case of human rabies in Wuhan, in May 2018. The patient had got a dog bite wound 3 years before symptoms of confusion, hydrophobia, and photophobia o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724148/ https://www.ncbi.nlm.nih.gov/pubmed/33318930 http://dx.doi.org/10.1016/j.idcr.2020.e00998 |
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author | Shengli, Meng Qian, Li Yan, Sun Wenjuan, Wu Jie, Wu Jinrong, Shi Zejun, Wang Xingguo, Li |
author_facet | Shengli, Meng Qian, Li Yan, Sun Wenjuan, Wu Jie, Wu Jinrong, Shi Zejun, Wang Xingguo, Li |
author_sort | Shengli, Meng |
collection | PubMed |
description | Rabies remains endemic in China and continues to pose a major threat to public health with a nearly 100 % case fatality rate in humans. We confirmed a case of human rabies in Wuhan, in May 2018. The patient had got a dog bite wound 3 years before symptoms of confusion, hydrophobia, and photophobia onset. On May 14, our laboratory confirmed that the patient was infected with a rabies virus that circulates in dogs in China and died on May 24, two weeks later after admission. Complete glycoprotein gene sequences determined for this isolate indicated the source of a RABV infection was dog-related RABV variants. |
format | Online Article Text |
id | pubmed-7724148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-77241482020-12-13 A case of human rabies with a long incubation period in Wuhan Shengli, Meng Qian, Li Yan, Sun Wenjuan, Wu Jie, Wu Jinrong, Shi Zejun, Wang Xingguo, Li IDCases Case Report Rabies remains endemic in China and continues to pose a major threat to public health with a nearly 100 % case fatality rate in humans. We confirmed a case of human rabies in Wuhan, in May 2018. The patient had got a dog bite wound 3 years before symptoms of confusion, hydrophobia, and photophobia onset. On May 14, our laboratory confirmed that the patient was infected with a rabies virus that circulates in dogs in China and died on May 24, two weeks later after admission. Complete glycoprotein gene sequences determined for this isolate indicated the source of a RABV infection was dog-related RABV variants. Elsevier 2020-11-04 /pmc/articles/PMC7724148/ /pubmed/33318930 http://dx.doi.org/10.1016/j.idcr.2020.e00998 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Shengli, Meng Qian, Li Yan, Sun Wenjuan, Wu Jie, Wu Jinrong, Shi Zejun, Wang Xingguo, Li A case of human rabies with a long incubation period in Wuhan |
title | A case of human rabies with a long incubation period in Wuhan |
title_full | A case of human rabies with a long incubation period in Wuhan |
title_fullStr | A case of human rabies with a long incubation period in Wuhan |
title_full_unstemmed | A case of human rabies with a long incubation period in Wuhan |
title_short | A case of human rabies with a long incubation period in Wuhan |
title_sort | case of human rabies with a long incubation period in wuhan |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724148/ https://www.ncbi.nlm.nih.gov/pubmed/33318930 http://dx.doi.org/10.1016/j.idcr.2020.e00998 |
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