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Axin-Mediated Regulation of Lifespan and Muscle Health in C. elegans Requires AMPK-FOXO Signaling

Aging is a significant risk factor for several diseases. Studies have uncovered multiple signaling pathways that modulate aging, including insulin/insulin-like growth factor-1 signaling (IIS). In Caenorhabditis elegans, the key regulator of IIS is DAF-16/FOXO. One of the kinases that affects DAF-16...

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Detalles Bibliográficos
Autores principales:	Mallick, Avijit, Ranawade, Ayush, van den Berg, Wouter, Gupta, Bhagwati P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724191/ https://www.ncbi.nlm.nih.gov/pubmed/33319173 http://dx.doi.org/10.1016/j.isci.2020.101843

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