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Quantification of the Resilience and Vulnerability of HIV-1 Native Glycan Shield at Atomistic Detail
Dense surface glycosylation on the HIV-1 envelope (Env) protein acts as a shield from the adaptive immune system. However, the molecular complexity and flexibility of glycans make experimental studies a challenge. Here we have integrated high-throughput atomistic modeling of fully glycosylated HIV-1...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724196/ https://www.ncbi.nlm.nih.gov/pubmed/33319171 http://dx.doi.org/10.1016/j.isci.2020.101836 |