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Calpains play an essential role in mechanical ventilation-induced diaphragmatic weakness and mitochondrial dysfunction
Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, an unintended consequence of prolonged MV is the rapid development of diaphragmatic atrophy and contractile dysfunction, known as ventilator-induced diaphragm dysfunction (VIDD). Although the m...
Autores principales: | Hyatt, Hayden W., Ozdemir, Mustafa, Yoshihara, Toshinori, Nguyen, Branden L., Deminice, Rafael, Powers, Scott K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724197/ https://www.ncbi.nlm.nih.gov/pubmed/33279868 http://dx.doi.org/10.1016/j.redox.2020.101802 |
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