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Calpains play an essential role in mechanical ventilation-induced diaphragmatic weakness and mitochondrial dysfunction

Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, an unintended consequence of prolonged MV is the rapid development of diaphragmatic atrophy and contractile dysfunction, known as ventilator-induced diaphragm dysfunction (VIDD). Although the m...

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Detalles Bibliográficos
Autores principales: Hyatt, Hayden W., Ozdemir, Mustafa, Yoshihara, Toshinori, Nguyen, Branden L., Deminice, Rafael, Powers, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724197/
https://www.ncbi.nlm.nih.gov/pubmed/33279868
http://dx.doi.org/10.1016/j.redox.2020.101802

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