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Is race or ethnicity associated with under‐utilization of statins among women in the United States: The study of women's health across the nation

BACKGROUND: Rates of statin use among minority women are unclear. HYPOTHESIS: We hypothesized that statin use would vary by race/ethnicity with lower rates among minority women compared with Whites. METHODS: Data from the study of women's health across the nation, a multiethnic cohort of women...

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Detalles Bibliográficos
Autores principales: Jackson, Elizabeth A., Ruppert, Kristine, Derby, Carol A., Lian, Yinjuan, Chae, Claudia U., Kazlauskaite, Rasa, Neal‐Perry, Genevieve, El Khoudary, Samar R., Harlow, Siobán D., Solomon, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724205/
https://www.ncbi.nlm.nih.gov/pubmed/32862481
http://dx.doi.org/10.1002/clc.23448
Descripción
Sumario:BACKGROUND: Rates of statin use among minority women are unclear. HYPOTHESIS: We hypothesized that statin use would vary by race/ethnicity with lower rates among minority women compared with Whites. METHODS: Data from the study of women's health across the nation, a multiethnic cohort of women collected between 2009 to 2011 were used to examine reported statin use by race/ethnicity and risk profile. Multivariable logistic modeling was performed to estimate the odds ratio (OR) of statin treatment. RESULTS: Of the 2399 women included, 234 had a diagnosis of atherosclerotic disease (ASCVD), 254 were diabetic (without ASCVD), 163 had an LDL ≥190 mg/dL, and 151 had a 10 year ASCVD pooled risk score ≥7.5%. Statins were used by 49.6% of women with CVD; 59.8% of women with diabetes without known ASCVD; 42.3% of women with an LDL ≥190 mg/dL; and 19.9% of women with an ASCVD risk ≥7.5%. Rates of statin use were 43.8% for women with ≥ two prior ASCVD events and 69.4% for women with ≥ one prior ASCVD event plus multiple high‐risk conditions. Among women eligible for statins, Black women had a significantly reduced adjusted odds of being on a statin (OR 0.53, 95% confidence interval [CI] 0.36‐0.78) compared with White women. CONCLUSIONS: In this cohort of multiethnic women, rates of statin use among women who would benefit were low, with Black women having lower odds of statin use than White women.