Cargando…

Outcome of catheter ablation in the very elderly‐insights from a large matched analysis

BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be perfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Willy, Kevin, Frommeyer, Gerrit, Dechering, Dirk G., Wasmer, Kristina, Höwel, Dennis, Welle, Sarah S., Bögeholz, Nils, Ellermann, Christian, Wolfes, Julian, Rath, Benjamin, Leitz, Patrick R., Köbe, Julia, Lange, Philipp S., Müller, Patrick, Reinke, Florian, Eckardt, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724238/
https://www.ncbi.nlm.nih.gov/pubmed/32865252
http://dx.doi.org/10.1002/clc.23455
_version_ 1783620503749001216
author Willy, Kevin
Frommeyer, Gerrit
Dechering, Dirk G.
Wasmer, Kristina
Höwel, Dennis
Welle, Sarah S.
Bögeholz, Nils
Ellermann, Christian
Wolfes, Julian
Rath, Benjamin
Leitz, Patrick R.
Köbe, Julia
Lange, Philipp S.
Müller, Patrick
Reinke, Florian
Eckardt, Lars
author_facet Willy, Kevin
Frommeyer, Gerrit
Dechering, Dirk G.
Wasmer, Kristina
Höwel, Dennis
Welle, Sarah S.
Bögeholz, Nils
Ellermann, Christian
Wolfes, Julian
Rath, Benjamin
Leitz, Patrick R.
Köbe, Julia
Lange, Philipp S.
Müller, Patrick
Reinke, Florian
Eckardt, Lars
author_sort Willy, Kevin
collection PubMed
description BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be performed safely regardless of the pts age. METHODS: We enrolled all pts aged >80 years (yrs) who underwent ablation for three different arrhythmias (atrial flutter [AFL], atrioventricular nodal re‐entry tachycardia [AVNRT], ventricular tachycardia [VT]) between August 2002 and December 2018. Procedural data and outcome were compared with matched groups aged 60 to 80 years and 40 to 60 years, respectively. Periprocedural and in‐hospital complications were analyzed. RESULTS: The analysis included 1191 patients (397 pts per group: 63% AFL, 23% AVNRT, 14% VT) who underwent ablation. Acute success was high in all types of arrhythmias irrespective of age (>80, 60‐80, 40‐60 years: AFL 97%/98%/98%, AVNRT 97%/95%/97%, VT 82%/86%/93%). Rate of periprocedural complications were similar in all groups treated for AFL and AVNRT. For VT ablations significant differences were noted between pts > 80 or 60 to 80 years and those aged 40‐60 years (16.1%/14.3%/3.6%). Most complications were infections and groin haematoma. No strokes, iatrogenic atrioventricular blocks and deaths related to the ablation occurred. CONCLUSION: Ablation appears safe in pts > 80 years. Success rates were comparable to matched younger cohorts. A significant difference was observed for VT patients.
format Online
Article
Text
id pubmed-7724238
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wiley Periodicals, Inc.
record_format MEDLINE/PubMed
spelling pubmed-77242382020-12-11 Outcome of catheter ablation in the very elderly‐insights from a large matched analysis Willy, Kevin Frommeyer, Gerrit Dechering, Dirk G. Wasmer, Kristina Höwel, Dennis Welle, Sarah S. Bögeholz, Nils Ellermann, Christian Wolfes, Julian Rath, Benjamin Leitz, Patrick R. Köbe, Julia Lange, Philipp S. Müller, Patrick Reinke, Florian Eckardt, Lars Clin Cardiol Clinical Investigations BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be performed safely regardless of the pts age. METHODS: We enrolled all pts aged >80 years (yrs) who underwent ablation for three different arrhythmias (atrial flutter [AFL], atrioventricular nodal re‐entry tachycardia [AVNRT], ventricular tachycardia [VT]) between August 2002 and December 2018. Procedural data and outcome were compared with matched groups aged 60 to 80 years and 40 to 60 years, respectively. Periprocedural and in‐hospital complications were analyzed. RESULTS: The analysis included 1191 patients (397 pts per group: 63% AFL, 23% AVNRT, 14% VT) who underwent ablation. Acute success was high in all types of arrhythmias irrespective of age (>80, 60‐80, 40‐60 years: AFL 97%/98%/98%, AVNRT 97%/95%/97%, VT 82%/86%/93%). Rate of periprocedural complications were similar in all groups treated for AFL and AVNRT. For VT ablations significant differences were noted between pts > 80 or 60 to 80 years and those aged 40‐60 years (16.1%/14.3%/3.6%). Most complications were infections and groin haematoma. No strokes, iatrogenic atrioventricular blocks and deaths related to the ablation occurred. CONCLUSION: Ablation appears safe in pts > 80 years. Success rates were comparable to matched younger cohorts. A significant difference was observed for VT patients. Wiley Periodicals, Inc. 2020-08-31 /pmc/articles/PMC7724238/ /pubmed/32865252 http://dx.doi.org/10.1002/clc.23455 Text en © 2020 The Authors. Clinical Cardiology published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Investigations
Willy, Kevin
Frommeyer, Gerrit
Dechering, Dirk G.
Wasmer, Kristina
Höwel, Dennis
Welle, Sarah S.
Bögeholz, Nils
Ellermann, Christian
Wolfes, Julian
Rath, Benjamin
Leitz, Patrick R.
Köbe, Julia
Lange, Philipp S.
Müller, Patrick
Reinke, Florian
Eckardt, Lars
Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title_full Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title_fullStr Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title_full_unstemmed Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title_short Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
title_sort outcome of catheter ablation in the very elderly‐insights from a large matched analysis
topic Clinical Investigations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724238/
https://www.ncbi.nlm.nih.gov/pubmed/32865252
http://dx.doi.org/10.1002/clc.23455
work_keys_str_mv AT willykevin outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT frommeyergerrit outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT decheringdirkg outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT wasmerkristina outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT howeldennis outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT wellesarahs outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT bogeholznils outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT ellermannchristian outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT wolfesjulian outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT rathbenjamin outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT leitzpatrickr outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT kobejulia outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT langephilipps outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT mullerpatrick outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT reinkeflorian outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis
AT eckardtlars outcomeofcatheterablationintheveryelderlyinsightsfromalargematchedanalysis