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Outcome of catheter ablation in the very elderly‐insights from a large matched analysis
BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be perfo...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724238/ https://www.ncbi.nlm.nih.gov/pubmed/32865252 http://dx.doi.org/10.1002/clc.23455 |
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author | Willy, Kevin Frommeyer, Gerrit Dechering, Dirk G. Wasmer, Kristina Höwel, Dennis Welle, Sarah S. Bögeholz, Nils Ellermann, Christian Wolfes, Julian Rath, Benjamin Leitz, Patrick R. Köbe, Julia Lange, Philipp S. Müller, Patrick Reinke, Florian Eckardt, Lars |
author_facet | Willy, Kevin Frommeyer, Gerrit Dechering, Dirk G. Wasmer, Kristina Höwel, Dennis Welle, Sarah S. Bögeholz, Nils Ellermann, Christian Wolfes, Julian Rath, Benjamin Leitz, Patrick R. Köbe, Julia Lange, Philipp S. Müller, Patrick Reinke, Florian Eckardt, Lars |
author_sort | Willy, Kevin |
collection | PubMed |
description | BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be performed safely regardless of the pts age. METHODS: We enrolled all pts aged >80 years (yrs) who underwent ablation for three different arrhythmias (atrial flutter [AFL], atrioventricular nodal re‐entry tachycardia [AVNRT], ventricular tachycardia [VT]) between August 2002 and December 2018. Procedural data and outcome were compared with matched groups aged 60 to 80 years and 40 to 60 years, respectively. Periprocedural and in‐hospital complications were analyzed. RESULTS: The analysis included 1191 patients (397 pts per group: 63% AFL, 23% AVNRT, 14% VT) who underwent ablation. Acute success was high in all types of arrhythmias irrespective of age (>80, 60‐80, 40‐60 years: AFL 97%/98%/98%, AVNRT 97%/95%/97%, VT 82%/86%/93%). Rate of periprocedural complications were similar in all groups treated for AFL and AVNRT. For VT ablations significant differences were noted between pts > 80 or 60 to 80 years and those aged 40‐60 years (16.1%/14.3%/3.6%). Most complications were infections and groin haematoma. No strokes, iatrogenic atrioventricular blocks and deaths related to the ablation occurred. CONCLUSION: Ablation appears safe in pts > 80 years. Success rates were comparable to matched younger cohorts. A significant difference was observed for VT patients. |
format | Online Article Text |
id | pubmed-7724238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wiley Periodicals, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77242382020-12-11 Outcome of catheter ablation in the very elderly‐insights from a large matched analysis Willy, Kevin Frommeyer, Gerrit Dechering, Dirk G. Wasmer, Kristina Höwel, Dennis Welle, Sarah S. Bögeholz, Nils Ellermann, Christian Wolfes, Julian Rath, Benjamin Leitz, Patrick R. Köbe, Julia Lange, Philipp S. Müller, Patrick Reinke, Florian Eckardt, Lars Clin Cardiol Clinical Investigations BACKGROUND: Ablation emerged as first line therapy in the treatment of various arrhythmias. Nevertheless, in older patients (pts), decision is often made pro drug treatment as more complications and less benefit are suspected. HYPOTHESIS: We hypothesized that different kind of ablations can be performed safely regardless of the pts age. METHODS: We enrolled all pts aged >80 years (yrs) who underwent ablation for three different arrhythmias (atrial flutter [AFL], atrioventricular nodal re‐entry tachycardia [AVNRT], ventricular tachycardia [VT]) between August 2002 and December 2018. Procedural data and outcome were compared with matched groups aged 60 to 80 years and 40 to 60 years, respectively. Periprocedural and in‐hospital complications were analyzed. RESULTS: The analysis included 1191 patients (397 pts per group: 63% AFL, 23% AVNRT, 14% VT) who underwent ablation. Acute success was high in all types of arrhythmias irrespective of age (>80, 60‐80, 40‐60 years: AFL 97%/98%/98%, AVNRT 97%/95%/97%, VT 82%/86%/93%). Rate of periprocedural complications were similar in all groups treated for AFL and AVNRT. For VT ablations significant differences were noted between pts > 80 or 60 to 80 years and those aged 40‐60 years (16.1%/14.3%/3.6%). Most complications were infections and groin haematoma. No strokes, iatrogenic atrioventricular blocks and deaths related to the ablation occurred. CONCLUSION: Ablation appears safe in pts > 80 years. Success rates were comparable to matched younger cohorts. A significant difference was observed for VT patients. Wiley Periodicals, Inc. 2020-08-31 /pmc/articles/PMC7724238/ /pubmed/32865252 http://dx.doi.org/10.1002/clc.23455 Text en © 2020 The Authors. Clinical Cardiology published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Investigations Willy, Kevin Frommeyer, Gerrit Dechering, Dirk G. Wasmer, Kristina Höwel, Dennis Welle, Sarah S. Bögeholz, Nils Ellermann, Christian Wolfes, Julian Rath, Benjamin Leitz, Patrick R. Köbe, Julia Lange, Philipp S. Müller, Patrick Reinke, Florian Eckardt, Lars Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title | Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title_full | Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title_fullStr | Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title_full_unstemmed | Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title_short | Outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
title_sort | outcome of catheter ablation in the very elderly‐insights from a large matched analysis |
topic | Clinical Investigations |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724238/ https://www.ncbi.nlm.nih.gov/pubmed/32865252 http://dx.doi.org/10.1002/clc.23455 |
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