Cargando…
The evolutionary history and global spatio-temporal dynamics of potato virus Y
Potato virus Y (PVY) is a destructive plant pathogen that causes considerable losses to global potato and tobacco production. Although the molecular structure of PVY is well characterized, the evolutionary and global transmission dynamics of this virus remain poorly understood. We investigated the p...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724251/ https://www.ncbi.nlm.nih.gov/pubmed/33324488 http://dx.doi.org/10.1093/ve/veaa056 |
_version_ | 1783620506129268736 |
---|---|
author | Gao, Fangluan Kawakubo, Shusuke Ho, Simon Y W Ohshima, Kazusato |
author_facet | Gao, Fangluan Kawakubo, Shusuke Ho, Simon Y W Ohshima, Kazusato |
author_sort | Gao, Fangluan |
collection | PubMed |
description | Potato virus Y (PVY) is a destructive plant pathogen that causes considerable losses to global potato and tobacco production. Although the molecular structure of PVY is well characterized, the evolutionary and global transmission dynamics of this virus remain poorly understood. We investigated the phylodynamics of the virus by analysing 253 nucleotide sequences of the genes encoding the third protein (P3), cylindrical inclusion protein (CI), and the nuclear inclusion protein (NIb). Our Bayesian phylogenetic analyses showed that the mean substitution rates of different regions of the genome ranged from 8.50 × 10(−5) to 1.34 × 10(−4) substitutions/site/year, whereas the time to the most recent common ancestor of PVY varied with the length of the genomic regions and with the number of viral isolates being analysed. Our phylogeographic analysis showed that the PVY population originated in South America and was introduced into Europe in the 19th century, from where it spread around the globe. The migration pathways of PVY correlate well with the trade routes of potato tubers, suggesting that the global spread of PVY is associated with human activities. |
format | Online Article Text |
id | pubmed-7724251 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-77242512020-12-14 The evolutionary history and global spatio-temporal dynamics of potato virus Y Gao, Fangluan Kawakubo, Shusuke Ho, Simon Y W Ohshima, Kazusato Virus Evol Research Article Potato virus Y (PVY) is a destructive plant pathogen that causes considerable losses to global potato and tobacco production. Although the molecular structure of PVY is well characterized, the evolutionary and global transmission dynamics of this virus remain poorly understood. We investigated the phylodynamics of the virus by analysing 253 nucleotide sequences of the genes encoding the third protein (P3), cylindrical inclusion protein (CI), and the nuclear inclusion protein (NIb). Our Bayesian phylogenetic analyses showed that the mean substitution rates of different regions of the genome ranged from 8.50 × 10(−5) to 1.34 × 10(−4) substitutions/site/year, whereas the time to the most recent common ancestor of PVY varied with the length of the genomic regions and with the number of viral isolates being analysed. Our phylogeographic analysis showed that the PVY population originated in South America and was introduced into Europe in the 19th century, from where it spread around the globe. The migration pathways of PVY correlate well with the trade routes of potato tubers, suggesting that the global spread of PVY is associated with human activities. Oxford University Press 2020-11-21 /pmc/articles/PMC7724251/ /pubmed/33324488 http://dx.doi.org/10.1093/ve/veaa056 Text en © The Author(s) 2020. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Gao, Fangluan Kawakubo, Shusuke Ho, Simon Y W Ohshima, Kazusato The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title | The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title_full | The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title_fullStr | The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title_full_unstemmed | The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title_short | The evolutionary history and global spatio-temporal dynamics of potato virus Y |
title_sort | evolutionary history and global spatio-temporal dynamics of potato virus y |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724251/ https://www.ncbi.nlm.nih.gov/pubmed/33324488 http://dx.doi.org/10.1093/ve/veaa056 |
work_keys_str_mv | AT gaofangluan theevolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT kawakuboshusuke theevolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT hosimonyw theevolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT ohshimakazusato theevolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT gaofangluan evolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT kawakuboshusuke evolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT hosimonyw evolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy AT ohshimakazusato evolutionaryhistoryandglobalspatiotemporaldynamicsofpotatovirusy |