Cargando…

Two Functional Axes of Feedback-Enforced PRC2 Recruitment in Mouse Embryonic Stem Cells

Polycomb Repressive Complex 2 (PRC2) plays an essential role in gene repression during development, catalyzing H3 lysine 27 trimethylation (H3K27me3). MTF2 in the PRC2.1 sub-complex, and JARID2 in PRC2.2, are central in core PRC2 recruitment to target genes in mouse embryonic stem cells (mESCs). To...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perino, Matteo, van Mierlo, Guido, Loh, Chet, Wardle, Sandra M.T., Zijlmans, Dick W., Marks, Hendrik, Veenstra, Gert Jan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724473/ https://www.ncbi.nlm.nih.gov/pubmed/32763159 http://dx.doi.org/10.1016/j.stemcr.2020.07.007

Ejemplares similares

Loss of PRC2 subunits primes lineage choice during exit of pluripotency
por: Loh, Chet H., et al.
Publicado: (2021)

The Role of Polycomb Proteins in Cell Lineage Commitment and Embryonic Development
por: Loh, Chet H., et al.
Publicado: (2022)

PRC1 uncomplexed
por: Schouten, Sanne, et al.
Publicado: (2022)

Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements
por: Kahn, Tatyana G., et al.
Publicado: (2016)

Independent domains for recruitment of PRC1 and PRC2 by human XIST
por: Dixon-McDougall, Thomas, et al.
Publicado: (2021)

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
por: Glancy, Eleanor, et al.
Publicado: (2023)

Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells
por: Aljazi, Mohammad B., et al.
Publicado: (2020)

Critical Role for P53 in Regulating the Cell Cycle of Ground State Embryonic Stem Cells
por: ter Huurne, Menno, et al.
Publicado: (2020)

Establishing the Embryonic Axes: Prime Time for Teratogenic Insults
por: Sadler, Thomas W.
Publicado: (2017)

EMBR-15. PRC2 COMPLEX ENFORCES NEURONAL LINEAGE AND SUPPRESSES TUMOR GROWTH IN SHH MEDULLOBLASTOMA
por: Cleveland, Abigail, et al.
Publicado: (2021)

PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells
por: Illingworth, Robert S., et al.
Publicado: (2012)

Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells
por: Zepeda-Martinez, J. A., et al.
Publicado: (2020)

Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
por: Sugishita, Hiroki, et al.
Publicado: (2021)

Cbx2 stably associates with mitotic chromosomes via a PRC2- or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes
por: Zhen, Chao Yu, et al.
Publicado: (2014)

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
por: Blackledge, Neil P., et al.
Publicado: (2014)

LncRNAs and PRC2: Coupled Partners in Embryonic Stem Cells
por: Fiorenzano, Alessandro, et al.
Publicado: (2019)

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus
por: Schorderet, Patrick, et al.
Publicado: (2013)

Race, gender, class, and sexual orientation: intersecting axes of inequality and self-rated health in Canada
por: Veenstra, Gerry
Publicado: (2011)

CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR
por: Sharma, Adhikarimayum Lakhikumar, et al.
Publicado: (2020)

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes
por: Soehnlein, Oliver, et al.
Publicado: (2013)

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells
por: Mendenhall, Eric M., et al.
Publicado: (2010)

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2
por: Davidovich, Chen, et al.
Publicado: (2015)

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
por: Wang, Xueyin, et al.
Publicado: (2017)

Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment
por: Cooper, Sarah, et al.
Publicado: (2014)

Oxidative damage and DNA repair in desiccated recalcitrant embryonic axes of Acer pseudoplatanus L.
por: Plitta-Michalak, Beata P., et al.
Publicado: (2022)

PRC2 binds to active promoters and contacts nascent RNAs in embryonic stem cells
por: Kaneko, Syuzo, et al.
Publicado: (2013)

Ybx1 fine-tunes PRC2 activities to control embryonic brain development
por: Evans, Myron K., et al.
Publicado: (2020)

The Economy Axe
Publicado: (1923)

PRC1 controls spindle polarization and recruitment of cytokinetic factors during monopolar cytokinesis
por: Shrestha, Sanjay, et al.
Publicado: (2012)

Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions
por: Nässel, Dick R., et al.
Publicado: (2020)

The Influence of Physical Fitness on Reasons for Academy Separation in Law Enforcement Recruits
por: Lockie, Robert G., et al.
Publicado: (2019)

Profiling the Typical Training Load of a Law Enforcement Recruit Class
por: Maupin, Danny, et al.
Publicado: (2022)

Transcriptome analysis uncovers key regulatory and metabolic aspects of soybean embryonic axes during germination
por: Bellieny-Rabelo, Daniel, et al.
Publicado: (2016)

PRC1 preserves epidermal tissue integrity independently of PRC2
por: Cohen, Idan, et al.
Publicado: (2019)

Structure and Function of the Polycomb Repressive Complexes PRC1 and PRC2
por: Angrand, Pierre-Olivier
Publicado: (2022)

Princeton: Budget axed
Publicado: (1970)

Axes in outer space
por: Handel, Michael, et al.
Publicado: (2012)

PRC1 sustains the integrity of neural fate in the absence of PRC2 function
por: Sawai, Ayana, et al.
Publicado: (2022)

Solid-State Biology and Seed Longevity: A Mechanical Analysis of Glasses in Pea and Soybean Embryonic Axes
por: Ballesteros, Daniel, et al.
Publicado: (2019)

Experimental duplication of bilaterian body axes in spider embryos: Holm’s organizer and self-regulation of embryonic fields
por: Oda, Hiroki, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u8sms5uo9q8cobpuhk7rvaa1pl