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Embryonic Stem Cell Differentiation Is Regulated by SET through Interactions with p53 and β-Catenin
The multifunctional histone chaperone, SET, is essential for embryonic development in the mouse. Previously, we identified SET as a factor that is rapidly downregulated during embryonic stem cell (ESC) differentiation, suggesting a possible role in the maintenance of pluripotency. Here, we explore S...
Autores principales: | Harikumar, Arigela, Lim, Patrick S.L., Nissim-Rafinia, Malka, Park, Jung Eun, Sze, Siu Kwan, Meshorer, Eran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724474/ https://www.ncbi.nlm.nih.gov/pubmed/33296674 http://dx.doi.org/10.1016/j.stemcr.2020.11.004 |
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