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A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis
Phagocytosis is a key function in various cells throughout the body. A deficiency in photoreceptor outer segment (POS) phagocytosis by the retinal pigment epithelium (RPE) causes vision loss in inherited retinal diseases and possibly age-related macular degeneration. To date, there are no effective...
Autores principales: | Schreiter, Sven, Vafia, Katerina, Barsacchi, Rico, Tsang, Stephen H., Bickle, Marc, Ader, Marius, Karl, Mike O., Tanaka, Elly M., Almedawar, Seba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724476/ https://www.ncbi.nlm.nih.gov/pubmed/33242397 http://dx.doi.org/10.1016/j.stemcr.2020.10.013 |
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