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Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs

[Image: see text] Although tyrosine kinase inhibitors (TKIs) have revolutionized cancer therapy in the past two decades, severe drawbacks such as strong adverse effects and drug resistance limit their clinical application. Prodrugs represent a valuable approach to overcoming these disadvantages by a...

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Detalles Bibliográficos
Autores principales:	Mathuber, Marlene, Schueffl, Hemma, Dömötör, Orsolya, Karnthaler, Claudia, Enyedy, Éva A., Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724630/ https://www.ncbi.nlm.nih.gov/pubmed/33222438 http://dx.doi.org/10.1021/acs.inorgchem.0c03083

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