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Role of Long-range Allosteric Communication in Determining the Stability and Disassembly of SARS-COV-2 in Complex with ACE2

Severe acute respiratory syndrome (SARS) and novel coronavirus disease (COVID-19) are caused by two closely related beta-coronaviruses, SARS-CoV and SARS-CoV-2, respectively. The envelopes surrounding these viruses are decorated with spike proteins, whose receptor binding domains (RBDs) initiate inv...

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Detalles Bibliográficos
Autores principales: Mugnai, Mauro L., Templeton, Clark, Elber, Ron, Thirumalai, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724663/
https://www.ncbi.nlm.nih.gov/pubmed/33299995
http://dx.doi.org/10.1101/2020.11.30.405340