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Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report

INTRODUCTION: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that can cause fatal tachyarrhythmias brought on by physical or emotional stress. There is little reported in the literature regarding management of CPVT in pregnancy much less during labor. CASE PRESENT...

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Autores principales: Schumer, Amy, Contag, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724802/
https://www.ncbi.nlm.nih.gov/pubmed/33292493
http://dx.doi.org/10.1186/s13256-020-02569-5
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author Schumer, Amy
Contag, Stephen
author_facet Schumer, Amy
Contag, Stephen
author_sort Schumer, Amy
collection PubMed
description INTRODUCTION: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that can cause fatal tachyarrhythmias brought on by physical or emotional stress. There is little reported in the literature regarding management of CPVT in pregnancy much less during labor. CASE PRESENTATION: A gravida 2, para 1 presented to our high-risk clinic at 15 weeks gestation with known CPVT. The Caucasian female patient had been diagnosed after experiencing a cardiac arrest following a motor vehicle accident and found to have a pathogenic cardiac ryanodine receptor mutation. An implantable cardioverter defibrillator was placed at that time. Her pregnancy was uncomplicated, and she was medically managed with metoprolol, flecainide, and verapamil. Her labor course and successful vaginal delivery were uncomplicated and involved a multidisciplinary team comprising specialists in electrophysiology, maternal fetal medicine, anesthesiology, general obstetrics, lactation, and neonatology. CONCLUSIONS: CPVT is likely underdiagnosed and, given that cardiovascular disease is a leading cause of death in pregnancy, it is important to bring further awareness to the diagnosis and management of this inherited arrhythmia syndrome in pregnancy.
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spelling pubmed-77248022020-12-09 Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report Schumer, Amy Contag, Stephen J Med Case Rep Case Report INTRODUCTION: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that can cause fatal tachyarrhythmias brought on by physical or emotional stress. There is little reported in the literature regarding management of CPVT in pregnancy much less during labor. CASE PRESENTATION: A gravida 2, para 1 presented to our high-risk clinic at 15 weeks gestation with known CPVT. The Caucasian female patient had been diagnosed after experiencing a cardiac arrest following a motor vehicle accident and found to have a pathogenic cardiac ryanodine receptor mutation. An implantable cardioverter defibrillator was placed at that time. Her pregnancy was uncomplicated, and she was medically managed with metoprolol, flecainide, and verapamil. Her labor course and successful vaginal delivery were uncomplicated and involved a multidisciplinary team comprising specialists in electrophysiology, maternal fetal medicine, anesthesiology, general obstetrics, lactation, and neonatology. CONCLUSIONS: CPVT is likely underdiagnosed and, given that cardiovascular disease is a leading cause of death in pregnancy, it is important to bring further awareness to the diagnosis and management of this inherited arrhythmia syndrome in pregnancy. BioMed Central 2020-12-09 /pmc/articles/PMC7724802/ /pubmed/33292493 http://dx.doi.org/10.1186/s13256-020-02569-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Schumer, Amy
Contag, Stephen
Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title_full Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title_fullStr Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title_full_unstemmed Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title_short Catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
title_sort catecholaminergic polymorphic ventricular tachycardia in pregnancy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724802/
https://www.ncbi.nlm.nih.gov/pubmed/33292493
http://dx.doi.org/10.1186/s13256-020-02569-5
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