Cargando…

Long non-coding RNA CDKN2B-AS1 regulates high glucose-induced human mesangial cell injury via regulating the miR-15b-5p/WNT2B axis

BACKGROUND: Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) has been reported to be related to diabetic nephropathy (DN) progression. However, the regulatory mechanisms of CDKN2B-AS1 in DN are unclear. METHODS: High glucose (HG) was used to induce human mesangia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Jing, Yu, Yanming, Fang, Zhan, He, Haiyan, Wang, Dan, Teng, Jian, Yang, Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724838/ https://www.ncbi.nlm.nih.gov/pubmed/33298110 http://dx.doi.org/10.1186/s13098-020-00618-z

Ejemplares similares

Long non‑coding RNA L13Rik promotes high glucose-induced mesangial cell hypertrophy and matrix protein expression by regulating miR-2861/CDKN1B axis
por: Sun, Linlin, et al.
Publicado: (2023)

LncRNA NEAT1 Promotes High Glucose-Induced Mesangial Cell Hypertrophy by Targeting miR-222-3p/CDKN1B Axis
por: Liao, Lin, et al.
Publicado: (2021)

LncRNA HOTAIR facilitates high glucose-induced mesangial cell proliferation, fibrosis and oxidative stress in diabetic nephropathy via regulating miR-147a/WNT2B axis
por: Wang, Xin, et al.
Publicado: (2022)

Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter
por: Ou, Minghui, et al.
Publicado: (2020)

CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-κB Inflammatory Signaling in Mesangial Cells
por: Li, Yanhui, et al.
Publicado: (2017)

Loss of Both CDKN2A and CDKN2B Allows for Centrosome Overduplication in Melanoma
por: Patel, Shyamal, et al.
Publicado: (2020)

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours.
por: Schmidt, E. E., et al.
Publicado: (1997)

Investigations on the Role of the MicroRNA-338-5p/Wnt Family Member 2B (WNT2B) Axis in Regulating the Pathogenesis of Nasopharyngeal Carcinoma (NPC)
por: Wang, Suzhen, et al.
Publicado: (2021)

Loss of CDKN2A and CDKN2B expression is associated with disease recurrence in oral cancer
por: Deepak Roshan, V G, et al.
Publicado: (2019)

WNT7A Regulation by miR-15b in Ovarian Cancer
por: MacLean, James A., et al.
Publicado: (2016)

Steap4 attenuates high glucose and S100B-induced effects in mesangial cells
por: Chuang, Chao-Tang, et al.
Publicado: (2015)

Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants
por: Houston, Douglas W., et al.
Publicado: (2022)

CDKN2B Methylation Correlates with Survival in AML Patients
por: Kamali Dolatabadi, Esmat, et al.
Publicado: (2017)

Roles of CDKN1B in cancer?
por: Belletti, Barbara, et al.
Publicado: (2015)

Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation
por: Adorno, Maddalena, et al.
Publicado: (2018)

Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis
por: Rathi, Sonika, et al.
Publicado: (2020)

Association of Myocardial Infarction with CDKN2B Antisense RNA 1 (CDKN2B-AS1) rs1333049 Polymorphism in Slovenian Subjects with Type 2 Diabetes Mellitus
por: Tibaut, Miha, et al.
Publicado: (2022)

Long Noncoding RNA CDKN2B-AS1 Facilitates Lung Cancer Development Through Regulating miR-378b/NR2C2
por: Wang, Guolei, et al.
Publicado: (2020)

Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B
por: Soto, José Luis, et al.
Publicado: (2005)

Abnormal epigenetic regulation of the gene expression levels of Wnt2b and Wnt7b: Implications for neural tube defects
por: BAI, BAOLING, et al.
Publicado: (2016)

Mysterious link between iron overload and CDKN2A/2B
por: Toyokuni, Shinya
Publicado: (2011)

Association Study of Genetic Variants in CDKN2A/CDKN2B Genes/Loci with Late-Onset Alzheimer's Disease
por: Tedde, Andrea, et al.
Publicado: (2011)

Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome
por: Chan, Sock Hoai, et al.
Publicado: (2016)

Promoter hypermethylation inactivates CDKN2A, CDKN2B and RASSF1A genes in sporadic parathyroid adenomas
por: Arya, Ashutosh Kumar, et al.
Publicado: (2017)

Knockdown of long non-coding RNA CDKN2B-AS1 suppresses the progression of breast cancer by miR-122-5p/STK39 axis
por: Qin, Shaojie, et al.
Publicado: (2021)

Long Non-Coding RNA CDKN2B-AS1 Facilitates Laryngeal Squamous Cell Cancer Through Regulating miR-497/CDK6 Pathway
por: Cui, Xiangyan, et al.
Publicado: (2019)

Novel germline variants of CDKN1B and CDKN2C identified during screening for familial primary hyperparathyroidism
por: Mazarico-Altisent, I., et al.
Publicado: (2022)

CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A
por: Tu, Q, et al.
Publicado: (2018)

The Yin and Yang-Like Clinical Implications of the CDKN2A/ARF/CDKN2B Gene Cluster in Acute Lymphoblastic Leukemia
por: González-Gil, Celia, et al.
Publicado: (2021)

Association of CDKN2A/CDKN2B Gene Polymorphisms with Increased Susceptibility to Intracranial Aneurysm in a Chinese Han Population
por: Cui, Xiaopeng, et al.
Publicado: (2021)

Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis
por: Thakur, Nanamika, et al.
Publicado: (2021)

Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B)
por: Gao, Peng, et al.
Publicado: (2017)

HMGB1 regulates ferroptosis through Nrf2 pathway in mesangial cells in response to high glucose
por: Wu, You, et al.
Publicado: (2021)

Sodium Glucose Cotransporter 2 (SGLT2) Plays as a Physiological Glucose Sensor and Regulates Cellular Contractility in Rat Mesangial Cells
por: Wakisaka, Masanori, et al.
Publicado: (2016)

FBW7 Regulates the Autophagy Signal in Mesangial Cells Induced by High Glucose
por: Gao, Chenlin, et al.
Publicado: (2019)

Long Non-coding RNA CDKN2B Antisense RNA 1 Gene Contributes to Paclitaxel Resistance in Endometrial Carcinoma
por: Shang, Chao, et al.
Publicado: (2019)

CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia
por: Jang, Woori, et al.
Publicado: (2019)

CDKN2B Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke
por: Zhou, Shuyu, et al.
Publicado: (2017)

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma
por: Hu, Zhenxian, et al.
Publicado: (2017)

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas
por: Sievers, Philipp, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_20endbpfuuh3sm3nn0c4o1cc4d