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Dissecting molecular mechanisms underlying H(2)O(2)-induced apoptosis of mouse bone marrow mesenchymal stem cell: role of Mst1 inhibition

BACKGROUND: Bone marrow mesenchymal stem cell (BM-MSC) has been shown to treat pulmonary arterial hypertension (PAH). However, excessive reactive oxygen species (ROS) increases the apoptosis of BM-MSCs, leading to poor survival and engraft efficiency. Thus, improving the ability of BM-MSCs to scaven...

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Detalles Bibliográficos
Autores principales:	Zhang, Qian, Cheng, Xianfeng, Zhang, Haizhou, Zhang, Tao, Wang, Zhengjun, Zhang, Wenlong, Yu, Wancheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724846/ https://www.ncbi.nlm.nih.gov/pubmed/33298178 http://dx.doi.org/10.1186/s13287-020-02041-7

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