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Allogeneic human umbilical cord Wharton’s jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo

BACKGROUND: The transplantation of human umbilical cord blood (UCB) CD34+ cells has been successfully used to treat hematological disorders but one major limitation has been the low cell numbers available. Mesenchymal stem cells (MSCs) lying within the bone marrow in vivo behave like a scaffold on w...

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Detalles Bibliográficos
Autores principales: Lin, Hao Daniel, Fong, Chui-Yee, Biswas, Arijit, Bongso, Ariff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724853/
https://www.ncbi.nlm.nih.gov/pubmed/33298170
http://dx.doi.org/10.1186/s13287-020-02048-0