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Three functional mutation sites affect the immune response of pigs through altering the expression pattern and IgV domain of the CD4 protein
BACKGROUND: The CD4 protein is an important surface marker of T lymphocytes, which can mediate the antigen presentation process by interacting with MHC II and TCR molecules in human and mouse. RESULTS: In this study, two haplotypes (A and B) of the CD4 gene were found within Chinese indigenous and W...
Autores principales: | Zhang, Weiya, Ni, Juan, Zhang, Jie, Zhang, Lu, Zhou, Huanhuan, Zhao, Changzhi, Zhu, Mengjin, Wang, Haiyan, Han, Jianlin, Li, Xinyun, Zhao, Shuhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724863/ https://www.ncbi.nlm.nih.gov/pubmed/33297958 http://dx.doi.org/10.1186/s12860-020-00333-7 |
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