Cargando…
Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer
BACKGROUND: Adenoviral vectors emerged as important platforms for cancer immunotherapy. Vaccination with adenoviral vectors is promising in this respect, however, their specific mechanisms of action are not fully understood. Here, we assessed the development and maintenance of vaccine-induced tumor-...
Autores principales: | van der Gracht, Esmé TI, Schoonderwoerd, Mark JA, van Duikeren, Suzanne, Yilmaz, Ayse N, Behr, Felix M, Colston, Julia M, Lee, Lian N, Yagita, Hideo, van Gisbergen, Klaas PJM, Hawinkels, Lukas JAC, Koning, Frits, Klenerman, Paul, Arens, Ramon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725098/ https://www.ncbi.nlm.nih.gov/pubmed/33293355 http://dx.doi.org/10.1136/jitc-2020-001133 |
Ejemplares similares
-
Memory CD8(+) T cell heterogeneity is primarily driven by pathogen-specific cues and additionally shaped by the tissue environment
por: van der Gracht, Esmé T.I., et al.
Publicado: (2020) -
PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors
por: Beyrend, Guillaume, et al.
Publicado: (2019) -
Functional Heterogeneity and Therapeutic Targeting of Tissue-Resident Memory T Cells
por: van der Gracht, Esmé T. I., et al.
Publicado: (2021) -
Delayed vaccine-induced CD8(+) T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication
por: van der Sluis, Tetje C, et al.
Publicado: (2023) -
Interleukin‐6‐mediated resistance to immunotherapy is linked to impaired myeloid cell function
por: Beyranvand Nejad, Elham, et al.
Publicado: (2020)