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Monocytes and Macrophages in Alpha-1 Antitrypsin Deficiency

Alpha-1 antitrypsin deficiency (AATD) is a genetic condition characterised by low circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor. The most common deficiency variants are the S and Z mutations, which cause the accumulation of misfolded AAT in hepatocytes resulting in e...

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Detalles Bibliográficos
Autores principales:	Belchamber, Kylie B R, Walker, Eloise M, Stockley, Robert A, Sapey, Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725100/ https://www.ncbi.nlm.nih.gov/pubmed/33311976 http://dx.doi.org/10.2147/COPD.S276792

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