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Targeted expression profiling reveals distinct stages of early canine fibroblast reprogramming are regulated by 2-oxoglutarate hydroxylases

BACKGROUND: Ectopic expression of a defined set of transcription factors allows the reprogramming of mammalian somatic cells to pluripotency. Despite continuous progress in primate and rodent reprogramming, limited attention has been paid to cell reprogramming in domestic and companion species. Prev...

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Detalles Bibliográficos
Autores principales: Tobias, Ian C., Kao, Mian-Mian C., Parmentier, Thomas, Hunter, Hailey, LaMarre, Jonathan, Betts, Dean H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725121/
https://www.ncbi.nlm.nih.gov/pubmed/33298190
http://dx.doi.org/10.1186/s13287-020-02047-1