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The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin

BACKGROUND: The huntingtin-associated protein 40 (HAP40) abundantly interacts with huntingtin (HTT), the protein that is altered in Huntington’s disease (HD). Therefore, we analysed the evolution of HAP40 and its interaction with HTT. RESULTS: We found that in amniotes HAP40 is encoded by a single-e...

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Detalles Bibliográficos
Autores principales:	Seefelder, Manuel, Alva, Vikram, Huang, Bin, Engler, Tatjana, Baumeister, Wolfgang, Guo, Qiang, Fernández-Busnadiego, Rubén, Lupas, Andrei N., Kochanek, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725122/ https://www.ncbi.nlm.nih.gov/pubmed/33297953 http://dx.doi.org/10.1186/s12862-020-01705-5

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