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Disruption of Plasmodium falciparum histidine-rich protein 2 may affect haem metabolism in the blood stage
BACKGROUND: Haem is a key metabolic factor in the life cycle of the malaria parasite. In the blood stage, the parasite acquires host haemoglobin to generate amino acids for protein synthesis and the by-product haem for metabolic use. The malaria parasite can also synthesize haem de novo on its own....
Autores principales: | Yang, Yingchao, Tang, Tongke, Feng, Bo, Li, Shanshan, Hou, Nan, Ma, Xiao, Jiang, Lubin, Xin, Xiaofang, Chen, Qijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725123/ https://www.ncbi.nlm.nih.gov/pubmed/33298142 http://dx.doi.org/10.1186/s13071-020-04460-0 |
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