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Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients

Background Marjolin’s ulcer (MU) of lower extremities usually presents with scar contracture and functional disability. They often follow an aggressive course and poor outcome, and require early radical removal. Split-thickness skin grafts, local flaps, or amputation are commonly practiced surgical...

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Autores principales: Sharma, Shobhit, Das, Nikhil, Gupta, Vivek, Bera, Sudipta, Bisht, Navneeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725200/
https://www.ncbi.nlm.nih.gov/pubmed/33312791
http://dx.doi.org/10.7759/cureus.11392
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author Sharma, Shobhit
Das, Nikhil
Gupta, Vivek
Bera, Sudipta
Bisht, Navneeta
author_facet Sharma, Shobhit
Das, Nikhil
Gupta, Vivek
Bera, Sudipta
Bisht, Navneeta
author_sort Sharma, Shobhit
collection PubMed
description Background Marjolin’s ulcer (MU) of lower extremities usually presents with scar contracture and functional disability. They often follow an aggressive course and poor outcome, and require early radical removal. Split-thickness skin grafts, local flaps, or amputation are commonly practiced surgical options for MU. Though free flaps are gaining popularity for various oncoplastic reconstruction, they are not frequently used for MU. A free anterolateral thigh (ALT) flap may have a beneficial role as it provides simultaneous coverage for a large defect after radical tumor and scar excision. Methods Between January 2015 and December 2018, 11 patients with lower limb MU reconstructed with free ALT flap were reviewed retrospectively for the surgical procedure, recurrences, and functional outcomes. Results Mean dimensions of the defect and flaps were 8 cm × 6 cm and 18.91 cm × 11 cm, respectively, and total flap coverage was obtained in nine cases. Marginal flap loss was noted in one and residual contracture in two cases. Functional improvement of the limb was achieved in all cases. Recurrence or disease-related mortality was not seen in any patient after a mean follow-up of 35.82 months. Conclusions Free ALT flap reconstruction of MU of extremity facilitates most radical tumor and scar-contracture removal and thus reduces the chances of re-ulceration. It facilitates local radiotherapy protocol with the provision of immediate durable coverage. Thus, it has a beneficial role other than a secondary reconstructive procedure. Moreover, an added benefit may be obtained with a “flow-through’ flap” to avoid amputation and improve functional outcomes.
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spelling pubmed-77252002020-12-10 Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients Sharma, Shobhit Das, Nikhil Gupta, Vivek Bera, Sudipta Bisht, Navneeta Cureus Plastic Surgery Background Marjolin’s ulcer (MU) of lower extremities usually presents with scar contracture and functional disability. They often follow an aggressive course and poor outcome, and require early radical removal. Split-thickness skin grafts, local flaps, or amputation are commonly practiced surgical options for MU. Though free flaps are gaining popularity for various oncoplastic reconstruction, they are not frequently used for MU. A free anterolateral thigh (ALT) flap may have a beneficial role as it provides simultaneous coverage for a large defect after radical tumor and scar excision. Methods Between January 2015 and December 2018, 11 patients with lower limb MU reconstructed with free ALT flap were reviewed retrospectively for the surgical procedure, recurrences, and functional outcomes. Results Mean dimensions of the defect and flaps were 8 cm × 6 cm and 18.91 cm × 11 cm, respectively, and total flap coverage was obtained in nine cases. Marginal flap loss was noted in one and residual contracture in two cases. Functional improvement of the limb was achieved in all cases. Recurrence or disease-related mortality was not seen in any patient after a mean follow-up of 35.82 months. Conclusions Free ALT flap reconstruction of MU of extremity facilitates most radical tumor and scar-contracture removal and thus reduces the chances of re-ulceration. It facilitates local radiotherapy protocol with the provision of immediate durable coverage. Thus, it has a beneficial role other than a secondary reconstructive procedure. Moreover, an added benefit may be obtained with a “flow-through’ flap” to avoid amputation and improve functional outcomes. Cureus 2020-11-09 /pmc/articles/PMC7725200/ /pubmed/33312791 http://dx.doi.org/10.7759/cureus.11392 Text en Copyright © 2020, Sharma et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Plastic Surgery
Sharma, Shobhit
Das, Nikhil
Gupta, Vivek
Bera, Sudipta
Bisht, Navneeta
Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title_full Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title_fullStr Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title_full_unstemmed Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title_short Lower Extremity Marjolin’s Ulcer Reconstruction With Free Anterolateral Thigh Flap: A Case Series of 11 Patients
title_sort lower extremity marjolin’s ulcer reconstruction with free anterolateral thigh flap: a case series of 11 patients
topic Plastic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725200/
https://www.ncbi.nlm.nih.gov/pubmed/33312791
http://dx.doi.org/10.7759/cureus.11392
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