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Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature

Chordoma is a sporadic type of cancer that affects the spine and is particularly challenging to treat due to the paucity of reported cases and scientific literature. In particular, primary chordomas affecting both the sacral and thoracic vertebrae are extremely rare. We herein report a rare case of...

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Autores principales: Bai, Rui, Zhao, Zhen-Qun, Wang, Yu-Xin, Zhao, Wei, Wu, Li-Shuan, Cui, Shu-Xia, Guo, Shi-Bing, Liang, Chen-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725214/
https://www.ncbi.nlm.nih.gov/pubmed/33363727
http://dx.doi.org/10.3892/mco.2020.2179
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author Bai, Rui
Zhao, Zhen-Qun
Wang, Yu-Xin
Zhao, Wei
Wu, Li-Shuan
Cui, Shu-Xia
Guo, Shi-Bing
Liang, Chen-Liang
author_facet Bai, Rui
Zhao, Zhen-Qun
Wang, Yu-Xin
Zhao, Wei
Wu, Li-Shuan
Cui, Shu-Xia
Guo, Shi-Bing
Liang, Chen-Liang
author_sort Bai, Rui
collection PubMed
description Chordoma is a sporadic type of cancer that affects the spine and is particularly challenging to treat due to the paucity of reported cases and scientific literature. In particular, primary chordomas affecting both the sacral and thoracic vertebrae are extremely rare. We herein report a rare case of chordoma in the sacral and thoracic vertebrae with pulmonary metastasis, along with a literature review. The objective of the present study was to explore treatment options and long-term outcomes in patients with metastatic chordoma. Posterior decompression was performed for the thoracic tumor, followed by extended resection of the sacral tumor. The symptoms of the patient were relieved after surgery, and the postoperative Nurick score decreased from grade 3 to grade 2, while the postoperative McCormick score was I. Therefore, complete chordoma excision and internal spinal fixation may effectively reduce tumor recurrence and metastasis.
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spelling pubmed-77252142020-12-23 Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature Bai, Rui Zhao, Zhen-Qun Wang, Yu-Xin Zhao, Wei Wu, Li-Shuan Cui, Shu-Xia Guo, Shi-Bing Liang, Chen-Liang Mol Clin Oncol Articles Chordoma is a sporadic type of cancer that affects the spine and is particularly challenging to treat due to the paucity of reported cases and scientific literature. In particular, primary chordomas affecting both the sacral and thoracic vertebrae are extremely rare. We herein report a rare case of chordoma in the sacral and thoracic vertebrae with pulmonary metastasis, along with a literature review. The objective of the present study was to explore treatment options and long-term outcomes in patients with metastatic chordoma. Posterior decompression was performed for the thoracic tumor, followed by extended resection of the sacral tumor. The symptoms of the patient were relieved after surgery, and the postoperative Nurick score decreased from grade 3 to grade 2, while the postoperative McCormick score was I. Therefore, complete chordoma excision and internal spinal fixation may effectively reduce tumor recurrence and metastasis. D.A. Spandidos 2021-01 2020-11-26 /pmc/articles/PMC7725214/ /pubmed/33363727 http://dx.doi.org/10.3892/mco.2020.2179 Text en Copyright: © Bai et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Bai, Rui
Zhao, Zhen-Qun
Wang, Yu-Xin
Zhao, Wei
Wu, Li-Shuan
Cui, Shu-Xia
Guo, Shi-Bing
Liang, Chen-Liang
Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title_full Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title_fullStr Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title_full_unstemmed Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title_short Sacral and thoracic chordoma with pulmonary metastases: A case report and review of the literature
title_sort sacral and thoracic chordoma with pulmonary metastases: a case report and review of the literature
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725214/
https://www.ncbi.nlm.nih.gov/pubmed/33363727
http://dx.doi.org/10.3892/mco.2020.2179
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