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Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China

BACKGROUND: Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. We aimed to evaluate the associations of circulating s...

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Detalles Bibliográficos
Autores principales: Yun, Huan, Sun, Liang, Wu, Qingqing, Zong, Geng, Qi, Qibin, Li, Huaixing, Zheng, He, Zeng, Rong, Liang, Liming, Lin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725305/
https://www.ncbi.nlm.nih.gov/pubmed/33296380
http://dx.doi.org/10.1371/journal.pmed.1003451