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A Rare Association Between Prostate Cancer and Polycythemia Vera

The association of polycythemia vera (PV) and localized prostate cancer is uncommon. PV is one of the myeloproliferative neoplasms that is characterized by an increased red cell mass and uncontrolled formation of blood cells owing to an acquired mutation in Janus kinase-2. PV has numerous complicati...

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Detalles Bibliográficos
Autores principales: Elhaj, Maab F, Yassin, Mohamed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725466/
https://www.ncbi.nlm.nih.gov/pubmed/33312802
http://dx.doi.org/10.7759/cureus.11404
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author Elhaj, Maab F
Yassin, Mohamed A
author_facet Elhaj, Maab F
Yassin, Mohamed A
author_sort Elhaj, Maab F
collection PubMed
description The association of polycythemia vera (PV) and localized prostate cancer is uncommon. PV is one of the myeloproliferative neoplasms that is characterized by an increased red cell mass and uncontrolled formation of blood cells owing to an acquired mutation in Janus kinase-2. PV has numerous complications and could raise the hazard of other tumors. Here, we report an extremely rare association of localized prostate cancer in a 62-year-old male with PV. He was treated by CyberKnife surgery and completed four doses of goserelin and radiotherapy, his follow up Magnetic Resonance Imaging (MRI) four months after completion of treatment showed no recurrence, and the PV was treated with hydroxyurea 500 mg twice per day and repeated phlebotomies, when needed, to keep his hematocrit level under 45%.
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spelling pubmed-77254662020-12-10 A Rare Association Between Prostate Cancer and Polycythemia Vera Elhaj, Maab F Yassin, Mohamed A Cureus Internal Medicine The association of polycythemia vera (PV) and localized prostate cancer is uncommon. PV is one of the myeloproliferative neoplasms that is characterized by an increased red cell mass and uncontrolled formation of blood cells owing to an acquired mutation in Janus kinase-2. PV has numerous complications and could raise the hazard of other tumors. Here, we report an extremely rare association of localized prostate cancer in a 62-year-old male with PV. He was treated by CyberKnife surgery and completed four doses of goserelin and radiotherapy, his follow up Magnetic Resonance Imaging (MRI) four months after completion of treatment showed no recurrence, and the PV was treated with hydroxyurea 500 mg twice per day and repeated phlebotomies, when needed, to keep his hematocrit level under 45%. Cureus 2020-11-09 /pmc/articles/PMC7725466/ /pubmed/33312802 http://dx.doi.org/10.7759/cureus.11404 Text en Copyright © 2020, Elhaj et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Elhaj, Maab F
Yassin, Mohamed A
A Rare Association Between Prostate Cancer and Polycythemia Vera
title A Rare Association Between Prostate Cancer and Polycythemia Vera
title_full A Rare Association Between Prostate Cancer and Polycythemia Vera
title_fullStr A Rare Association Between Prostate Cancer and Polycythemia Vera
title_full_unstemmed A Rare Association Between Prostate Cancer and Polycythemia Vera
title_short A Rare Association Between Prostate Cancer and Polycythemia Vera
title_sort rare association between prostate cancer and polycythemia vera
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725466/
https://www.ncbi.nlm.nih.gov/pubmed/33312802
http://dx.doi.org/10.7759/cureus.11404
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