Late endosomes promote microglia migration via cytosolic translocation of immature protease cathD

Organelle transport requires dynamic cytoskeleton remodeling, but whether cytoskeletal dynamics are, in turn, regulated by organelles remains elusive. Here, we demonstrate that late endosomes, a type of prelysosomal organelles, facilitate actin-cytoskeleton remodeling via cytosolic translocation of...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Jun, Zhang, Ting, Cheng, Daxiao, Yang, Junhua, Chen, Sicong, Wang, Xingyue, Li, Xia, Duan, Duo, Lou, Huifang, Zhu, Liya, Luo, Jianhong, Ho, Margaret S., Wang, Xiao-Dong, Duan, Shumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725477/
https://www.ncbi.nlm.nih.gov/pubmed/33298434
http://dx.doi.org/10.1126/sciadv.aba5783

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