Cargando…

Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity

Ferroptosis is a recently discovered iron-dependent form of oxidative programmed cell death distinct from caspase-dependent apoptosis. In this study, we investigated the effect of ferroptosis in neomycin-induced hair cell loss by using selective ferroptosis inhibitor liproxstatin-1 (Lip-1). Cell via...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Zhiwei, Tang, Dongmei, Zhao, Liping, Li, Wen, Han, Jinghong, Hu, Bing, Nie, Guohui, He, Yingzi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725559/ https://www.ncbi.nlm.nih.gov/pubmed/33343803 http://dx.doi.org/10.1155/2020/1782659

Ejemplares similares

Erratum to “Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity”
por: Zheng, Zhiwei, et al.
Publicado: (2021)

Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells
por: Gao, Song, et al.
Publicado: (2020)

c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro
por: Yu, Xiaoyu, et al.
Publicado: (2017)

Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro
por: He, Zuhong, et al.
Publicado: (2016)

Inhibition of ferroptosis protects House Ear Institute‐Organ of Corti 1 cells and cochlear hair cells from cisplatin‐induced ototoxicity
por: Mei, Honglin, et al.
Publicado: (2020)

The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells
por: Zhao, Junling, et al.
Publicado: (2022)

Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro
por: Guan, Ming, et al.
Publicado: (2016)

Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell
por: Gong, Liang, et al.
Publicado: (2022)

Increased mitochondrial DNA copy number protects hair cells and HEI-OC1 cells against drug-induced apoptosis
por: Mei, Honglin, et al.
Publicado: (2020)

Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity
por: Zhao, Xiaochang, et al.
Publicado: (2021)

Protective effect of tanshinone IIA against radiation-induced ototoxicity in HEI-OC1 cells
por: DU, SHASHA, et al.
Publicado: (2013)

Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult
por: Chen, Yan, et al.
Publicado: (2013)

The Contribution of Immune Infiltrates to Ototoxicity and Cochlear Hair Cell Loss
por: Wood, Megan B., et al.
Publicado: (2017)

Ceramide-1-phosphate protection of cochlear hair cells against cisplatin ototoxicity
por: Le, Quang, et al.
Publicado: (2016)

Differentiation of embryonic stem cells into a putative hair cell-progenitor cells via co-culture with HEI-OC1 cells
por: Carpena, Nathaniel T., et al.
Publicado: (2021)

Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells
por: Mwangi, Martin, et al.
Publicado: (2017)

Nrf2 Knockout Affected the Ferroptosis Signaling Pathway against Cisplatin-Induced Hair Cell-Like HEI-OC1 Cell Death
por: Wang, Weilong, et al.
Publicado: (2022)

PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway
por: Zhang, Yanzhuo, et al.
Publicado: (2021)

NLRX1 accelerates cisplatin-induced ototoxity in HEI-OC1 cells via promoting generation of ROS and activation of JNK signaling pathway
por: Yin, Haiyan, et al.
Publicado: (2017)

In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period
por: Sun, Shan, et al.
Publicado: (2014)

Poly ADP-Ribose Polymerase-1 inhibition by 3-aminobenzamide recuperates HEI-OC1 auditory hair cells from blast overpressure-induced cell death
por: Krishnan Muthaiah, Vijaya Prakash, et al.
Publicado: (2023)

Hair Cell Protection from Ototoxic Drugs
por: Wu, Peng, et al.
Publicado: (2021)

Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity
por: Davis, Samantha N., et al.
Publicado: (2020)

STK33 alleviates gentamicin‐induced ototoxicity in cochlear hair cells and House Ear Institute‐Organ of Corti 1 cells
por: Zhou, Meijuan, et al.
Publicado: (2018)

Autophagy protects auditory hair cells against neomycin-induced damage
por: He, Zuhong, et al.
Publicado: (2017)

Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage
por: Zhong, Zhenhua, et al.
Publicado: (2020)

Mechanisms of Aminoglycoside Ototoxicity and Targets of Hair Cell Protection
por: Huth, M. E., et al.
Publicado: (2011)

Identifying the mechanisms underlying the protective effect of tetramethylpyrazine against cisplatin-induced in vitro ototoxicity in HEI-OC1 auditory cells using gene expression profiling
por: Guan, Guofang, et al.
Publicado: (2020)

Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration
por: Warchol, Mark E., et al.
Publicado: (2021)

Rosmarinic Acid, Active Component of Dansam-Eum Attenuates Ototoxicity of Cochlear Hair Cells through Blockage of Caspase-1 Activity
por: Jeong, Hyun-Ja, et al.
Publicado: (2011)

Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage
por: Li, He, et al.
Publicado: (2018)

Protective Role of Trimetazidine Against Neomycin-induced Hair Cell Damage in Zebrafish
por: Chang, Jiwon, et al.
Publicado: (2013)

Ephrin A2 protein expression in the regeneration and plasticity of cochlear hair cells in chicken following kanamycin ototoxicity★
por: Yu, Jia, et al.
Publicado: (2012)

NaHS Protects Cochlear Hair Cells from Gentamicin-Induced Ototoxicity by Inhibiting the Mitochondrial Apoptosis Pathway
por: Dong, Yaodong, et al.
Publicado: (2015)

Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway
por: Quan, Yizhou, et al.
Publicado: (2015)

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity
por: Gonçalves, Ana Cláudia, et al.
Publicado: (2019)

Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity
por: Alharazneh, Abdelrahman, et al.
Publicado: (2011)

NPC1 Deficiency Contributes to Autophagy-Dependent Ferritinophagy in HEI-OC1 Auditory Cells
por: Liang, Lihong, et al.
Publicado: (2022)

Otoprotective Effects of Fucoidan Reduce Cisplatin-Induced Ototoxicity in Mouse Cochlear UB/OC-2 Cells
por: Hsieh, Cheng-Yu, et al.
Publicado: (2023)

Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival
por: Lin, Shelly C. Y., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8dthhc80nhn562i0kfad2t2cbm