Cargando…

Co-expression Network Analysis Reveals Novel Genes Underlying Alzheimer’s Disease Pathogenesis

Background: The pathogenesis of Alzheimer’s disease (AD) remains to be elucidated. This study aimed to identify the hub genes in AD pathogenesis and determine their functions and pathways. Methods: A co-expression network for an AD gene dataset with 401 samples was constructed, and the AD status-rel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Rui-ting, Yu, Qian, Zhou, Shao-dan, Yin, Yi-xin, Hu, Rui-guang, Lu, Hai-peng, Hu, Bang-li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725685/ https://www.ncbi.nlm.nih.gov/pubmed/33324198 http://dx.doi.org/10.3389/fnagi.2020.605961

Ejemplares similares

Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease
por: Wang, Xin, et al.
Publicado: (2017)

Alzheimer’s Disease: From Pathogenesis to Mesenchymal Stem Cell Therapy – Bridging the Missing Link
por: Hu, Jingqiong, et al.
Publicado: (2022)

Circulating extracellular vesicle-containing microRNAs reveal potential pathogenesis of Alzheimer’s disease
por: Wang, Yi, et al.
Publicado: (2022)

Multidimensional Face Representation in a Deep Convolutional Neural Network Reveals the Mechanism Underlying AI Racism
por: Tian, Jinhua, et al.
Publicado: (2021)

Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
por: Franks, Katherine H., et al.
Publicado: (2015)

Loss of Parietal Memory Network Integrity in Alzheimer’s Disease
por: Hu, Yang, et al.
Publicado: (2019)

Histone Acetylation Modifiers in the Pathogenesis of Alzheimer’s Disease
por: Lu, Xi, et al.
Publicado: (2015)

The Anatomo-Electrical Network Underlying Hypermotor Seizures
por: Wang, Xiu, et al.
Publicado: (2018)

Erosion of Gene Co-expression Networks Reveal Deregulation of Immune System Processes in Late-Onset Alzheimer’s Disease
por: Malamon, John Stephen, et al.
Publicado: (2020)

Current understanding of metal ions in the pathogenesis of Alzheimer’s disease
por: Wang, Lu, et al.
Publicado: (2020)

Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease
por: von Bernhardi, Rommy, et al.
Publicado: (2015)

Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications
por: Liu, Jun-Lin, et al.
Publicado: (2018)

Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis
por: Chakravorty, Anushka, et al.
Publicado: (2019)

The Eminent Role of microRNAs in the Pathogenesis of Alzheimer's Disease
por: Samadian, Mohammad, et al.
Publicado: (2021)

Most Pathways Can Be Related to the Pathogenesis of Alzheimer’s Disease
por: Morgan, Sarah L., et al.
Publicado: (2022)

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
por: Miao, Jifei, et al.
Publicado: (2023)

Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway
por: Wei, Wei, et al.
Publicado: (2023)

The effects of attention in auditory–visual integration revealed by time-varying networks
por: Jiang, Yuhao, et al.
Publicado: (2023)

Changes in Resting-State Functional Connectivity of Cerebellum in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: A Case-Control Study
por: Zhou, Zhi, et al.
Publicado: (2021)

Corrigendum: Changes in Resting-State Functional Connectivity of Cerebellum in Amnestic Mild Cognitive Impairment and Alzheimer's Disease: A Case-Control Study
por: Zhou, Zhi, et al.
Publicado: (2021)

Exploration of combined physical activity and music for patients with Alzheimer’s disease: A systematic review
por: Li, Kailimi, et al.
Publicado: (2022)

The Fourth Element Targeting Hypothesis of Alzheimer's Disease Pathogenesis and Pathophysiology
por: Kuljiš, Rodrigo O.
Publicado: (2010)

Tau Clearance Mechanisms and Their Possible Role in the Pathogenesis of Alzheimer Disease
por: Chesser, Adrianne S., et al.
Publicado: (2013)

Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease
por: Ohno, Masuo
Publicado: (2014)

The Role of Exosomes as Mediators of Neuroinflammation in the Pathogenesis and Treatment of Alzheimer’s Disease
por: Weng, Shiting, et al.
Publicado: (2022)

An Attention-Based CoT-ResNet With Channel Shuffle Mechanism for Classification of Alzheimer’s Disease Levels
por: Li, Chao, et al.
Publicado: (2022)

Regional Brain Fusion: Graph Convolutional Network for Alzheimer's Disease Prediction and Analysis
por: Li, Wenchao, et al.
Publicado: (2022)

The cognitive dysfunction of claustrum on Alzheimer’s disease: A mini-review
por: Chen, Chun-Yan, et al.
Publicado: (2023)

Comprehensive transcript-level analysis reveals transcriptional reprogramming during the progression of Alzheimer’s disease
por: Wu, Hao, et al.
Publicado: (2023)

Role of endoplasmic reticulum Ca2+ signaling in the pathogenesis of Alzheimer disease
por: Popugaeva, Elena, et al.
Publicado: (2013)

Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome
por: Andrews, Elizabeth J., et al.
Publicado: (2022)

Transcriptional Dysregulation Study Reveals a Core Network Involving the Progression of Alzheimer's Disease
por: Meng, Guofeng, et al.
Publicado: (2019)

The Role of Iron-Induced Fibrin in the Pathogenesis of Alzheimer’s Disease and the Protective Role of Magnesium
por: Lipinski, Boguslaw, et al.
Publicado: (2013)

Molecular Mechanisms for Herpes Simplex Virus Type 1 Pathogenesis in Alzheimer’s Disease
por: Harris, Steven A., et al.
Publicado: (2018)

The Role of Chronic Inflammatory Bone and Joint Disorders in the Pathogenesis and Progression of Alzheimer's Disease
por: Culibrk, Robert A., et al.
Publicado: (2020)

The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
por: Wu, Hongle, et al.
Publicado: (2022)

Excessive/Aberrant and Maladaptive Synaptic Plasticity: A Hypothesis for the Pathogenesis of Alzheimer’s Disease
por: Kawabata, Shigeki
Publicado: (2022)

Novel molecular mechanisms in Alzheimer’s disease: The potential role of DEK in disease pathogenesis
por: Greene, Allie N., et al.
Publicado: (2022)

Decoding the role of gut microbiota in Alzheimer’s pathogenesis and envisioning future therapeutic avenues
por: Liang, Junyi, et al.
Publicado: (2023)

Alterations of Graphic Properties and Related Cognitive Functioning Changes in Mild Alzheimer’s Disease Revealed by Individual Morphological Brain Network
por: Li, Wan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_53b4565f0utch1venh46qgdv88