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A Functional Comparison of Homopentameric Nicotinic Acetylcholine Receptors (ACR-16) Receptors From Necator americanus and Ancylostoma ceylanicum

Effective control of hookworm infections in humans and animals relies on using a small group of anthelmintics. Many of these drugs target cholinergic ligand-gated ion channels, yet the direct activity of anthelmintics has only been studied in a subset of these receptors, primarily in the non-parasit...

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Detalles Bibliográficos
Autores principales: Kaji, Mark D., Geary, Timothy G., Beech, Robin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725692/
https://www.ncbi.nlm.nih.gov/pubmed/33324163
http://dx.doi.org/10.3389/fnmol.2020.601102