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Evolution of HLA-F and its orthologues in primate species: a complex tale of conservation, diversification and inactivation

HLA-F represents one of the nonclassical MHC class I molecules in humans. Its main characteristics involve low levels of polymorphism in combination with a restricted tissue distribution. This signals that the gene product executes a specialised function, which, however, is still poorly understood....

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Detalles Bibliográficos
Autores principales: Otting, N., de Groot, N. G., Bontrop, R. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725694/
https://www.ncbi.nlm.nih.gov/pubmed/33184728
http://dx.doi.org/10.1007/s00251-020-01187-1