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Evolution of HLA-F and its orthologues in primate species: a complex tale of conservation, diversification and inactivation
HLA-F represents one of the nonclassical MHC class I molecules in humans. Its main characteristics involve low levels of polymorphism in combination with a restricted tissue distribution. This signals that the gene product executes a specialised function, which, however, is still poorly understood....
Autores principales: | Otting, N., de Groot, N. G., Bontrop, R. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725694/ https://www.ncbi.nlm.nih.gov/pubmed/33184728 http://dx.doi.org/10.1007/s00251-020-01187-1 |
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