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The interplay of dissolution, solution crystallization and solid-state transformation of amorphous indomethacin in aqueous solution
Supersaturation profiles of amorphous indomethacin in aqueous solution containing 0.4 wt% and 4 wt% of isopropanol were predicted by combining separately-determined kinetics for dissolution, solution crystallization, and solid-state transformation. The kinetics of solid-state transformation were mea...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725739/ https://www.ncbi.nlm.nih.gov/pubmed/33319209 http://dx.doi.org/10.1016/j.ijpx.2020.100063 |