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Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances

Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to sta...

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Autores principales: Pavlovska, Ilona, Klavina, Aneka, Auce, Agris, Vanadzins, Ivars, Silova, Alise, Komarovska, Laura, Silamikele, Baiba, Dobkevica, Linda, Paegle, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725781/
https://www.ncbi.nlm.nih.gov/pubmed/33299027
http://dx.doi.org/10.1038/s41598-020-78498-6
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author Pavlovska, Ilona
Klavina, Aneka
Auce, Agris
Vanadzins, Ivars
Silova, Alise
Komarovska, Laura
Silamikele, Baiba
Dobkevica, Linda
Paegle, Linda
author_facet Pavlovska, Ilona
Klavina, Aneka
Auce, Agris
Vanadzins, Ivars
Silova, Alise
Komarovska, Laura
Silamikele, Baiba
Dobkevica, Linda
Paegle, Linda
author_sort Pavlovska, Ilona
collection PubMed
description Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.
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spelling pubmed-77257812020-12-14 Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances Pavlovska, Ilona Klavina, Aneka Auce, Agris Vanadzins, Ivars Silova, Alise Komarovska, Laura Silamikele, Baiba Dobkevica, Linda Paegle, Linda Sci Rep Article Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services. Nature Publishing Group UK 2020-12-09 /pmc/articles/PMC7725781/ /pubmed/33299027 http://dx.doi.org/10.1038/s41598-020-78498-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pavlovska, Ilona
Klavina, Aneka
Auce, Agris
Vanadzins, Ivars
Silova, Alise
Komarovska, Laura
Silamikele, Baiba
Dobkevica, Linda
Paegle, Linda
Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_full Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_fullStr Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_full_unstemmed Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_short Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_sort assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725781/
https://www.ncbi.nlm.nih.gov/pubmed/33299027
http://dx.doi.org/10.1038/s41598-020-78498-6
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