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Control of Complement Activation by the Long Pentraxin PTX3: Implications in Age-Related Macular Degeneration

Dysregulation of the complement system is central to age-related macular degeneration (AMD), the leading cause of blindness in the developed world. Most of the genetic variation associated with AMD resides in complement genes, with the greatest risk associated with polymorphisms in the complement fa...

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Detalles Bibliográficos
Autores principales:	Stravalaci, Matteo, Davi, Francesca, Parente, Raffaella, Gobbi, Marco, Bottazzi, Barbara, Mantovani, Alberto, Day, Anthony J., Clark, Simon J., Romano, Mario R., Inforzato, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725797/ https://www.ncbi.nlm.nih.gov/pubmed/33324220 http://dx.doi.org/10.3389/fphar.2020.591908

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