BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma

Cancer stem cells (CSCs) define a subpopulation of cancer cells that are resistant to therapy. However, little is known of how CSC characteristics are regulated. We previously showed that dormant cancer stem cells are enriched with a CD274(low) fraction of cholangiocarcinoma cells. Here we found tha...

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Detalles Bibliográficos
Autores principales: Tamai, Keiichi, Nakamura-Shima, Mao, Shibuya-Takahashi, Rie, Kanno, Shin-Ichiro, Yasui, Akira, Mochizuki, Mai, Iwai, Wataru, Wakui, Yuta, Abue, Makoto, Yamamoto, Kuniharu, Miura, Koh, Mizuma, Masamichi, Unno, Michiaki, Kawamura, Sadafumi, Sato, Ikuro, Yasuda, Jun, Yamaguchi, Kazunori, Sugamura, Kazuo, Satoh, Kennichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725823/
https://www.ncbi.nlm.nih.gov/pubmed/33299012
http://dx.doi.org/10.1038/s41598-020-78539-0

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