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microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy

IgA nephropathy (IgAN) is the most common primary glomerular disease. The characteristic pathology involves immune complexes formed by the deposition of IgA1 and underglycosylated IgA1 aggregates in the mesangial area, which may be accompanied by the deposition of IgG and/or IgM and complement compo...

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Detalles Bibliográficos
Autores principales: Liu, Chan, Ye, Mu-Yao, Yan, Wen-Zhe, Peng, Xiao-Fei, He, Li-Yu, Peng, You-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725902/
https://www.ncbi.nlm.nih.gov/pubmed/33324395
http://dx.doi.org/10.3389/fimmu.2020.563699

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