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Macrophage Activation in the Synovium of Healthy and Osteoarthritic Equine Joints

Synovitis is a major component of osteoarthritis and is driven primarily by macrophages. Synovial macrophages are crucial for joint homeostasis (M2-like phenotype), but induce inflammation (M1-like) when regulatory functions become overwhelmed. Macrophage phenotypes in synovium from osteoarthritic a...

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Detalles Bibliográficos
Autores principales: Menarim, Bruno C., Gillis, Kiersten H., Oliver, Andrea, Ngo, Ying, Werre, Stephen R., Barrett, Sarah H., Rodgerson, Dwayne H., Dahlgren, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726135/
https://www.ncbi.nlm.nih.gov/pubmed/33324696
http://dx.doi.org/10.3389/fvets.2020.568756