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A comparison of AAV-vector production methods for gene therapy and preclinical assessment

Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of specific molecular targets, characterize various cellular functions, and model central nervous system (CNS) diseases. In therapeutic application...

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Detalles Bibliográficos
Autores principales: Davidsson, Marcus, Negrini, Matilde, Hauser, Swantje, Svanbergsson, Alexander, Lockowandt, Marcus, Tomasello, Giuseppe, Manfredsson, Fredric P., Heuer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726153/
https://www.ncbi.nlm.nih.gov/pubmed/33299011
http://dx.doi.org/10.1038/s41598-020-78521-w

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