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The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review

INTRODUCTION: Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignan...

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Autores principales: Jandou, Issam, Moataz, Amine, Mouqtassid, Mohammed Hicham, Dakir, Mohammed, Debbagh, Adil, Aboutaieb, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726245/
https://www.ncbi.nlm.nih.gov/pubmed/33395912
http://dx.doi.org/10.1016/j.ijscr.2020.11.132
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author Jandou, Issam
Moataz, Amine
Mouqtassid, Mohammed Hicham
Dakir, Mohammed
Debbagh, Adil
Aboutaieb, Rachid
author_facet Jandou, Issam
Moataz, Amine
Mouqtassid, Mohammed Hicham
Dakir, Mohammed
Debbagh, Adil
Aboutaieb, Rachid
author_sort Jandou, Issam
collection PubMed
description INTRODUCTION: Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. CASE PRESENTATION: We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. DISCUSSION: Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring. CONCLUSION: Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. It is a pathology that presents a diagnostic and therapeutic dilemma in which patients require regular and prolonged postoperative monitoring to detect a possible metastasis or recurrence.
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spelling pubmed-77262452020-12-13 The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review Jandou, Issam Moataz, Amine Mouqtassid, Mohammed Hicham Dakir, Mohammed Debbagh, Adil Aboutaieb, Rachid Int J Surg Case Rep Case Report INTRODUCTION: Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. CASE PRESENTATION: We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. DISCUSSION: Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring. CONCLUSION: Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. It is a pathology that presents a diagnostic and therapeutic dilemma in which patients require regular and prolonged postoperative monitoring to detect a possible metastasis or recurrence. Elsevier 2020-12-02 /pmc/articles/PMC7726245/ /pubmed/33395912 http://dx.doi.org/10.1016/j.ijscr.2020.11.132 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Jandou, Issam
Moataz, Amine
Mouqtassid, Mohammed Hicham
Dakir, Mohammed
Debbagh, Adil
Aboutaieb, Rachid
The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title_full The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title_fullStr The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title_full_unstemmed The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title_short The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
title_sort ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726245/
https://www.ncbi.nlm.nih.gov/pubmed/33395912
http://dx.doi.org/10.1016/j.ijscr.2020.11.132
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