Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT

Allogeneic hematopoietic stem cell transplantation is a potentially curative procedure for many malignant diseases. Donor T cells prevent disease recurrence via graft-versus-leukemia (GVL) effect. Donor T cells also contribute to graft-versus-host disease (GVHD), a debilitating and potentially fatal...

Descripción completa

Detalles Bibliográficos
Autores principales: Mammadli, Mahinbanu, Huang, Weishan, Harris, Rebecca, Sultana, Aisha, Cheng, Ying, Tong, Wei, Pu, Jeffery, Gentile, Teresa, Dsouza, Shanti, Yang, Qi, Bah, Alaji, August, Avery, Karimi, Mobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726260/
https://www.ncbi.nlm.nih.gov/pubmed/33324410
http://dx.doi.org/10.3389/fimmu.2020.593863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726260/
https://www.ncbi.nlm.nih.gov/pubmed/33324410
http://dx.doi.org/10.3389/fimmu.2020.593863

Ejemplares similares