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Amantadine Alleviates Postoperative Cognitive Dysfunction Possibly by Preserving Neurotrophic Factor Expression and Dendritic Arborization in the Hippocampus of Old Rodents

OBJECTIVES: Amantadine has been shown to attenuate postoperative learning and memory dysfunction in young adult rats. However, postoperative cognitive dysfunction often occurs in elderly patients. We aimed to determine whether amantadine attenuated postoperative learning and memory dysfunction and w...

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Detalles Bibliográficos
Autores principales: Zhong, Jing, Li, Jun, Ni, Cheng, Zuo, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726433/
https://www.ncbi.nlm.nih.gov/pubmed/33324197
http://dx.doi.org/10.3389/fnagi.2020.605330