Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling

Cannabinoid 1 receptor (CB1R) expression is upregulated in the liver with viral hepatitis, cirrhosis, and both alcoholic and non-alcoholic fatty liver disease (FLD), whereas its expression is muted under usual physiological conditions. Inhibiting CB1R has been shown to be beneficial in preserving he...

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Detalles Bibliográficos
Autores principales: Kim, Yoo, Gautam, Sudeep, Aseer, Kanikkai Raja, Kim, Jaekwan, Chandrasekaran, Prabha, Mazucanti, Caio Henrique, Ghosh, Paritosh, O’Connell, Jennifer F., Doyle, Máire E., Appleton, Ashley, Lehrmann, Elin, Liu, Qing-Rong, Egan, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726564/
https://www.ncbi.nlm.nih.gov/pubmed/33298885
http://dx.doi.org/10.1038/s41419-020-03261-8

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