In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations

The rapid progress achieved in the development of many biopharmaceuticals had a tremendous impact on the therapy of many metabolic/genetic disorders. This type of fruitful approach, called protein replacement therapy (PRT), aimed to either replace the deficient or malfunctional protein in human tiss...

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Detalles Bibliográficos
Autores principales: Kaiafas, Georgios C., Papagiannopoulou, Dionysia, Miliotou, Αndroulla N., Tsingotjidou, Anastasia S., Chalkidou, Parthenopi C., Tsika, Aikaterini C., Spyroulias, George A., Tsiftsoglou, Asterios S., Papadopoulou, Lefkothea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726716/
https://www.ncbi.nlm.nih.gov/pubmed/33318931
http://dx.doi.org/10.1016/j.ymgmr.2020.100683

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